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Lace Riggs

Neuroscience (UMB)

Area of Doctoral Study: Neuroscience
Undergraduate Institute: California State University, San Bernardino

Research Advisor: Todd D. Gould, M.D.

Description of Research

A lack of effective treatment options for major depression leads to prolonged suffering, substance abuse, and in some cases, attempted or completed suicide. Examining the etiological factors that enhance disease susceptibility, and improving our characterization of compounds with known efficacy, may provide mechanistic insight in favor of advancing novel therapeutic development. In the Gould Lab, I am currently using electrophysiological, pharmacological, and behavioral approaches to investigate the mechanistic basis for the rapid antidepressant actions of (R,S)-ketamine and its active metabolite, (2R,6R)-hydroxynorketamine.