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John Giddens

Biochemistry (UMB)

Area of Doctoral Study: Biochemistry and Molecular Biology
Undergraduate Institute: College of William and Mary

Research Advisor: Dr. Lai-Xi Wang

Description of Research

My project is focused on the chemoenzymatic synthesis of homogenous glycopeptides and glycoproteins using bacterial enzymes. The main glycoprotein target is IgG which is an important biological therapeutic and the carbohydrates attached directly affect the function and stability of these monoclonal antibodies.