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Florika Macazo, Ph.D.

Macazo_Florika

Chemistry and Biochemistry 2016

Area of Doctoral Study: Chemistry

Undergraduate Institute: University of the Philippines Diliman

Graduate Institute: University of the Philippines Diliman

Research Advisor: Ryan J. White, Ph.D.

Current Position: Postdoctoral Fellow, University of Utah

Description of Research

The title of my dissertation project is  “Building Glass Nanopore Sensors using Hsc70 for Specific and Quantitative Detection of ATP” , which involves constructing a glass nanopore (GNP) sensor using Hsc70 as the biorecognition element, and is targeted to perform sensitive, selective, specific, and quantitative detection of adenosine triphosphate (ATP). In the presence of ATP, this Hsc70-GNP sensor should be able to respond directly and specifically to ATP molecules, allowing for its sensitive quantification. Overal,l these Hsc70-GNP sensors should present a rapid, sensitive, selective, high-throughput, and specific analytical sensing method that can be employed in real-time monitoring of neurochemical cell communications occurring in the brain via the quantification of ATP.